Publikationen

     - 20132012 - 2011 - 2010 - 2009 - 2008 - 2007 - 2006 - 2005 -  

 

Publikationen 2013

 Journalbeiträge

 

  1. Beck J, Bierau S, Balzer S, Andag R, Kanzow P, Schmitz J, Gaedcke J, Moerer O, Slotta JE, Walson P, Kollmar O, Oellerich M, Schütz E. Digital Droplet PCR for Rapid Quantification of Donor DNA in the Circulation of Transplant Recipients as a Potential Universal Biomarker of Graft Injury. Clin Chem. 2013 Sep 23.
  2. Binder L, Schwörer H, Hoppe S, Streit F, Neumann S, Beckmann A, Wachter R, Oellerich M, Walson PD. Pharmacokinetics of meropenem in critically ill patients with severe infections. Ther Drug Monit. 2013 Feb;35(1):63-70.
  3. Biswas S, Sharmas, Saroha A, Bhakuni DS, Malhotra R, Zahur M, Oellerich M, Das HR, Asif AR. Identification of novel autoantigen in the synovial fluid of rheumatoid arthritis patients using an immunoproteomics approach. PLoS One. 2013;8(2):e56246.
  4. Brandhorst G, Weigand S, Eberle C, Raddatz D, Karaus M, Oellerich M, Walson PD. CD4+ immune response as a potential biomarker of patient reported inflammatory bowel disease (IBD) activity. Clin Chim Acta. 2013 Jun 5;421:31-3.
  5. Dieks JK, Gawinecka J, Asif AR, Varges D, Gmitterova K, Streich JH, Dihazi H, Heinemann U, Zerr I. Low-abundant CSF proteome alterations in dementia with Lewy bodies. J Alzheimers Dis. 2013 Jan 1;34(2):387-97.
  6. Dihazi H, Bohrer R, Jahn O, Lenz C, Majcherczyk A, Schmidt B, Urlaub H, Valerius O, Asif AR. Mass spectrometry imaging: linking molecule profiles to tissue spatial distribution. Expert Rev Proteomics. 2013 Feb;10(1):17-20.
  7. Dihazi H, Dihazi GH, Bibi A, Eltoweissy M, Mueller CA, Asif AR, Rubel D, Vasko R, Mueller GA. ERP57 secretion is important for extracellular matrix accumulation and renal fibrosis progression and is an earlier sign of disease onset. J Cell Sci. 2013 Aug 15;126(Pt 16):3649-63.
  8. Edelmann F, Wachter R, Schmidt AG, Kraigher-Krainer E, Colantonio C, Kamke W, Duvinage A, Stahrenberg R, Durstewitz K, Löffler M, Düngen HD, Tschöpe C, Herrmann-Lingen C, Halle M, Hasenfuss G, Gelbrich G, Pieske B; Aldo-DHF Investigators. Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial. JAMA. 2013 Feb 27;309(8):781-91.
  9. Gawinecka J, Nowak M, Carimalo J, Cardone F, Asif AR, Wemheuer WM, Schulz-Schaeffer WJ, Pocchiari M, Zerr I. Subtype-Specific Synaptic Proteome Alterations in Sporadic Creutzfeldt-Jakob Disease. J Alzheimers Dis. 2013 Jan 1;37(1):51-61.
  10. Luers C, Sutcliffe A, Binder L, Irle S, Pieske B. NT-proANP and NT-proBNP as prognostic markers in patients with acute decompensated heart failure of different etiologies. Clin Biochem. 2013 Aug;46(12):1013-9.
  11. Mushtaq A, Tariq MZ, Rashid U, Afroz A, Zeeshan N, Asif AR, Zahur M. Estimation of HCV viral load and liver enzymes among different patients groups of District Gujrat, Pakistan. Advances in Bioscience and Biotechnology, 2013, 4, 866-8714: 10.4236/abb.2013.49115
  12. Pešić I, Müller GA, Baumann C, Dihazi GH, Koziolek MJ, Eltoweissy M, Bramlage C, Asif AR, Dihazi H. Cellulose membranes are more effective in holding back vital proteins and exhibit less interaction with plasma proteins during hemodialysis. Biochim Biophys Acta. 2013 Apr;1834(4):754-62
  13. Petrova DT, Cocisiu GA, Eberle C, Rhode KH, Brandhorst G, Walson PD, Oellerich M. Can the Roche hemolysis index be used for automated determination of cell-free hemoglobin? A comparison to photometric assays. Clin Biochem. 2013 Sep;46(13-14):1298-301.
  14. Schumacher J, Ramljak S, Asif AR, Schaffrath M, Zischler H, Herlyn H. Evolutionary Conservation of Mammalian Sperm Proteins Associates with Overall, but not with Tyrosine Phosphorylation in Human Spermatozoa. J Proteome Res. 2013 Aug 6. (IN PRESS)
  15. von Eckardstein A, Roth HJ, Jones G, Preston S, Szekeres T, Imdahl R, Conti M, Blanckaert N, Jose D, Thiery J, Feldmann L, von Ahsen N, Locatelli M, Kremastinou J, Kunst A, Hubbuch A, McGovern M. cobas 8000 Modular analyzer series evaluated under routine-like conditions at 14 sites in Australia, Europe, and the United States. J Lab Autom. 2013 Aug;18(4):306-27.
  16. Wagner NM, Brandhorst G, Czepluch F, Lankeit M, Eberle C, Herzberg S, Faustin V, Riggert J, Oellerich M, Hasenfuss G, Konstantinides S, Schäfer K. Circulating regulatory T cells are reduced in obesity and may identify subjects at increased metabolic and cardiovascular risk. Obesity (Silver Spring). 2013 Mar;21(3):461-8.
  17. Zahid S, Khan R, Oellerich M, Ahmed N, Asif AR. Differential S-nitrosylation of proteins in Alzheimer's disease. Neuroscience. 2013 Oct 21. (IN PRESS)
  18. Zahur M, Asif MA, Zeeshan N, SMehmood S, Malik MF, Asif AR. Homeobox leucine zipper proteins and cotton improvement. Advances in Bioscience and Biotechnology, 2013, 4, 15-20.

 

 

Publikationen 2012

 Journalbeiträge

 

  1. Schulz-Juergensen S, Burdelski MM, Oellerich M, Brandhorst G (2012). Intracellular ATP production in CD4+ T cells as a predictor for infection and allograft rejection in trough-level guided pediatric liver transplant recipients under calcineurin-inhibitor therapy. Ther Drug Monit. Feb;34(1):4-10.
  2. Strasser D, Neumann K, Bergmann H, Marakalala MJ, Guler R, Rojowska A, Hopfner KP, Brombacher F, Urlaub H, Baier G, Brown GD, Leitges M, Ruland J (2012). Syk kinase-coupled C-type lectin receptors engage protein kinase C-s to elicit Card9 adaptor-mediated innate immunity. Immunity. Jan 27;36(1):32-42.
  3. Schmitzová J, Rasche N, Dybkov O, Kramer K, Fabrizio P, Urlaub H, Lührmann R, Pena V (2012). Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO J. Mar 9;31(9):2222-34.
  4. Alkhaja AK, Jans DC, Nikolov M, Vukotic M, Lytovchenko O, Ludewig F, Schliebs W, Riedel D, Urlaub H, Jakobs S, Deckers M (2012). MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell. Jan;23(2):247-57.
  5. Lemeer S, Kunold E, Klaeger S, Raabe M, Towers MW, Claudes E, Arrey TN, Strupat K, Urlaub H, Kuster B (2012). Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score. Anal Bioanal Chem. Jan;402(1):249-60.
  6. Zahid S, Oellerich M, Asif AR, Ahmed N (2012). Phosphoproteome profiling of substantia nigra and cortex regions of Alzheimer's disease patients. J Neurochem. Mar 21. [Epub ahead of print]
  7. Israeli M, Klein T, Brandhorst G, Oellerich M (2012). Confronting the challenge: Individualized immune monitoring after organ transplantation using the cellular immune function assay. Clin Chim Acta. Feb 3. [Epub ahead of print]
  8. Rother A, Glander P, Vitt E, Czock D, von Ahsen N, Armstrong VW, Oellerich M, Budde K, Feneberg R, Tönshoff B, Weber LT (2012). Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid. Eur J Clin Pharmacol. Jun;68(6):913-22. Epub 2012 Jan 25.
  9. Brandhorst G, Oellerich M, Maine G, Taylor P, Veen G, Wallemacq P (2012). Liquid chromatography-tandem mass spectrometry or automated immunoassays: what are the future trends in therapeutic drug monitoring? Clin Chem. May;58(5):821-5. Epub 2012 Jan 17
  10. Edelmann F, Tomaschitz A, Wachter R, Gelbrich G, Knoke M, Düngen HD, Pilz S, Binder L, Stahrenberg R, Schmidt A, März W, Pieske B (2012). Serum aldosterone and its relationship to left ventricular structure and geometry in patients with preserved left ventricular ejection fraction. Eur Heart J. Jan;33(2):203-12. Epub 2011 Aug 19.
  11. Emami-Nemini A, Gohla A, Urlaub H, Lohse MJ, Klenk C (2012). The Guanine Nucleotide Exchange Factor vav2 is a Negative Regulator of PTH-receptor / Gq-signaling. Mol Pharmacol. May 3. [Epub ahead of print]

 

 

Publikationen 2011

 Journalbeiträge

 

  1. Brakemann T, Stiel AC, Weber G, Andresen M, Testa I, Grotjohann T, Leutenegger M, Plessmann U, Urlaub H, Eggeling C, Wahl MC, Hell SW, Jakobs S (2011) A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. NAT BIOTECHNOL, 29(10): 942-7.
  2. Brandhorst G, Engelmayer J, Götze S, Oellerich M, von Ahsen N (2011) Pre-analytical effects of different lithium heparin plasma separation tubes in the routine clinical chemistry laboratory. CLIN CHEM LAB MED, 49(9): 1473-7.
  3. Brandhorst G, Oellerich M, Brunet M, Kowalski R, Vinks A, Wallemacq P (2011) Individually tailored immunosuppression: is there a role for biomarkers? CLIN CHEM, 57(3): 376-81.
  4. Brandhorst G, Streit F, Kratzsch J, Schiettecatte J, Roth HJ, Luppa PB, Körner A, Kiess W, Binder L, Oellerich M, von Ahsen N (2011) Multicenter evaluation of a new automated electrochemiluminescence immunoassay for the quantification of testosterone compared to liquid chromatography tandem mass spectrometry. Clin Biochem (Internet-Ausgabe), 44(2-3): 264-7.
  5. Chan A, Gold R, von Ahsen N (2011) ATP-binding cassette transporters in inflammatory brain disease. Curr Pharm Design (Internet-Ausgabe), 17(26): 2803-7.
  6. Dihazi H, Dihazi GH, Mueller C, Lahrichi L, Asif AR, Bibi A, Eltoweissy M, Vasko R, Mueller GA (2011) Proteomics characterization of cell model with renal fibrosis phenotype: osmotic stress as fibrosis triggering factor. J PROTEOMICS, 74(3): 304-18.
  7. Dihazi H, Dihazi GH, Jahn O, Meyer S, Nolte J, Asif AR, Mueller GA, Engel W (2011) Multipotent adult germline stem cells and embryonic stem cells functional proteomics revealed an important role of eukaryotic initiation factor 5A (Eif5a) in stem cell differentiation. J PROTEOME RES, 10(4): 1962-73.
  8. Edelmann F, Gelbrich G, Düngen HD, Fröhling S, Wachter R, Stahrenberg R, Binder L, Töpper A, Lashki DJ, Schwarz S, Herrmann-Lingen C, Löffler M, Hasenfuss G, Halle M, Pieske B (2011) Exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction: results of the Ex-DHF (Exercise training in Diastolic Heart Failure) pilot study. J AM COLL CARDIOL, 58(17): 1780-91.
  9. Edelmann F, Stahrenberg R, Polzin F, Kockskämper A, Düngen HD, Duvinage A, Binder L, Kunde J, Scherer M, Gelbrich G, Hasenfuss G, Pieske B, Wachter R, Herrmann-Lingen C (2011) Impaired physical quality of life in patients with diastolic dysfunction associates more strongly with neurohumoral activation than with echocardiographic parameters: quality of life in diastolic dysfunction. Am Heart J (Internet-Ausgabe), 161(4): 797-804.
  10. Ehrenreich H, Kästner A, Weissenborn K, Streeter J, Sperling S, Wang KK, Worthmann H, Hayes RL, Von Ahsen N, Kastrup A, Jeromin A, Herrmann M (2011) Circulating damage marker profiles support a neuroprotective effect of erythropoietin in ischemic stroke patients. Mol Med (Internet-Ausgabe), epub ahead of print: doi: 10.2119/molmed.2011.00259.
  11. Ertmer C, Mardin WA, Brüwer M, Schiller M, Kemper S, von Ahsen N, Hahnenkamp K (2011) Severe immunosuppression in inflammatory bowel disease: opening the floodgates to opportunists? Int J Colorectal Dis (Internet-Ausgabe), 26(12): 1625-7.
  12. Geisen C, Luxembourg B, Watzka M, Toennes SW, Sittinger K, Marinova M, von Ahsen N, Lindhoff-Last E, Seifried E, Oldenburg J (2011) Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters. Eur J Clin Pharmacol (Internet-Ausgabe), 67(4): 371-81.
  13. Hruzik A, Asif AR, Gross U (2011) Identification of Toxoplasma gondii SUB1 antigen as a marker for acute infection by use of an innovative evaluation method. J CLIN MICROBIOL, 49(7): 2419-25.
  14. Krumova P, Meulmeester E, Garrido M, Tirard M, Hsiao HH, Bossis G, Urlaub H, Zweckstetter M, Kügler S, Melchior F, Bähr M, Weishaupt JH (2011) Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol (Internet-Ausgabe), 194(1): 49-60.
  15. Lin SS, Blume M, von Ahsen N, Gross U, Bohne W (2011) Extracellular Toxoplasma gondii tachyzoites do not require carbon source uptake for ATP maintenance, gliding motility and invasion in the first hour of their extracellular life. INT J PARASITOL, 41(8): 835-41.
  16. Meyer T, Stanske B, Kochen MM, Cordes A, Yüksel I, Wachter R, Lüers C, Scherer M, Binder L, Pieske B, Herrmann-Lingen C (2011) Serum levels of interleukin-6 and interleukin-10 in relation to depression scores in patients with cardiovascular risk factors. BEHAV MED, 37(3): 105-12.
  17. Nikolov M, Stützer A, Mosch K, Krasauskas A, Soeroes S, Stark H, Urlaub H, Fischle W (2011) Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Mol Cell Proteomics (Internet-Ausgabe), 10(11): M110.005371.
  18. Norozi K, Buchhorn R, Yasin A, Geyer S, Binder L, Seabrook JA, Wessel A (2011) Growth differentiation factor 15: an additional diagnostic tool for the risk stratification of developing heart failure in patients with operated congenital heart defects? Am Heart J (Internet-Ausgabe), 162(1): 131-5.
  19. Oellerich T, Bremes V, Neumann K, Bohnenberger H, Dittmann K, Hsiao HH, Engelke M, Schnyder T, Batista FD, Urlaub H, Wienands J (2011) The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. Embo J (Internet-Ausgabe), 30(17): 3620-34.
  20. Petrova DT, Brehmer F, Schultze FC, Asif AR, Gross O, Oellerich M, Brandhorst G (2011) Differential kidney proteome profiling in a murine model of renal fibrosis under treatment with mycophenolate mofetil. PATHOBIOLOGY, 78(3): 162-70.
  21. Pidoux G, Witczak O, Jarnæss E, Myrvold L, Urlaub H, Stokka AJ, Küntziger T, Taskén K (2011) Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. Embo J (Internet-Ausgabe), 30(21): 4371-86.
  22. Prémaud A, Weber LT, Tönshoff B, Armstrong VW, Oellerich M, Urien S, Marquet P, Rousseau A (2011) Population pharmacokinetics of mycophenolic acid in pediatric renal transplant patients using parametric and nonparametric approaches. PHARMACOL RES, 63(3): 216-24.
  23. Qasim M, Rahman H, Oellerich M, Asif AR (2011) Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment. PROTEOME SCI, 9: 57.
  24. Rahman H, Qasim M, Schultze FC, Oellerich M, Asif AR (2011) Fetal calf serum heat inactivation and lipopolysaccharide contamination influence the human T lymphoblast proteome and phosphoproteome. PROTEOME SCI, 9(1): 71.
  25. Rossenbach J, Mueller GA, Lange K, Armstrong VW, Schmitto JD, Hintze E, Helfmann J, Konstantinides S, Koziolek MJ (2011) Lipid-apheresis improves microcirculation of the upper limbs. J Clin Apheresis (Internet-Ausgabe), 26(4): 167-73.
  26. Schnyder T, Castello A, Feest C, Harwood NE, Oellerich T, Urlaub H, Engelke M, Wienands J, Bruckbauer A, Batista FD (2011) B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. IMMUNITY, 34(6): 905-18.
  27. Stahrenberg R, Edelmann F, Mende M, Kockskämper A, Düngen HD, Scherer M, Kochen MM, Binder L, Herrmann-Lingen C, Gelbrich G, Hasenfuß G, Pieske B, Wachter R (2011) Association of glucose metabolism with diastolic function along the diabetic continuum. Correction to vol 53, pg 1331, 2010. DIABETOLOGIA, 54(4): 990.
  28. Streit F, Binder L, Hafke A, Brandhorst G, Braulke F, Haase D, Armbrust T, Cameron S, Ramadori G, Oellerich M, Walson P (2011) Use of total and unbound imatinib and metabolite LC-MS/MS assay to understand individual responses in CML and GIST patients. THER DRUG MONIT, 33(5): 632-43.
  29. van Gelder T, Silva HT, de Fijter H, Budde K, Kuypers D, Mamelok RD, Armstrong VW, Oellerich M (2011) How delayed graft function impacts exposure to mycophenolic acid in patients after renal transplantation. THER DRUG MONIT, 33(2): 155-64.
  30. Varges D, Jung K, Gawinecka J, Heinemann U, Schmitz M, von Ahsen N, Krasnianski A, Armstrong VW, Zerr I (2011) Amyloid- 1-42 Levels are Modified by Apolipoprotein E 4 in Creutzfeldt-Jakob Disease in a Similar Manner as in Alzheimer's disease. J ALZHEIMERS DIS, 23: 717-26.
  31. Vasko R, Mueller GA, von Jaschke AK, Asif AR, Dihazi H (2011) Impact of cisplatin administration on protein expression levels in renal cell carcinoma: a proteomic analysis. EUR J PHARMACOL, 670(1): 50-7.
  32. von Ahsen N, Wittwer CT, Schütz E (2011) Monovalent and divalent salt correction algorithms for Tm prediction--recommendations for Primer3 usage. BRIEF BIOINFORM, 12(5): 514-7.
  33. Wakeel A, Asif AR, Pitann B, Schubert S (2011) Proteome analysis of sugar beet (Beta vulgaris L.) elucidates constitutive adaptation during the first phase of salt stress. J PLANT PHYSIOL, 168(6): 519-26.
  34. Wand S, Waeschle R, Von Ahsen N, Hawighorst T, Bräuer A, Quintel M (2011) Case report: acute liver failure due to acute fatty liver of pregnancy. MINERVA ANESTESIOL, Epub ahead of print: Jun 17.
  35. Zafar S, von Ahsen N, Oellerich M, Zerr I, Schulz-Schaeffer WJ, Armstrong VW, Asif AR (2011) Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells. J PROTEOME RES, 10(7): 3123-35.
  36. Zutt M, Krüger U, Rosenberger A, Schön M, Neumann C, von Ahsen N, Kretschmer L (2011) Thrombophilia in patients with chronic venous leg ulcers-a study on patients with or without post-thrombotic syndrome. J Eur Acad Dermatol (Internet-Ausgabe), EarlyView: 1-8.
  37. Zutt M, Krüger U, Rosenberger A, Schön MP, Neumann C, von Ahsen N, Kretschmer L (2011) Increased Lipoprotein (a) concentrations in patients with chronic venous leg ulcers: a study on patients with or without postthrombotic syndrome. WOUND REPAIR REGEN, 19(2): 168-72.

 Medical Theses

  1. Brehmer F, Dr. med., Der Einfluss von Mycophenolat-Mofetil (MMF) auf die renale Fibrogenese: Bedeutung für neue therapeutische Ansätze. Dissertation Universität Göttingen 2011.
  2. Schultze F, Dr. med., Durch Sirolimus induzierte frühe Veränderungen des Proteoms und Phosphoproteoms in humanen T-Lymphoblasten. Dissertation Universität Göttingen 2011.

 PhD Theses

  1. Zafar S, Dr. rer. nat., Cellular Prion Protein (PrPc): Identification and Characterization of Novel Interacting Partners. Dissertation Universität Göttingen 2011.

 

 

Publikationen 2010

 Journalbeiträge

 

  1. Agarwal NK, Mueller GA, Mueller C, Streich JH, Asif AR, Dihazi H (2010) Expression proteomics of acute promyelocytic leukaemia cells treated with methotrexate. BIOCHIM BIOPHYS ACTA, -: -.
  2. Asif AR, Oellerich M, Amstrong VW, Gross U, Reichard U (2010) Analysis of the cellular Aspergillus fumigatus proteome that reacts with sera from rabbits developing an acquired immunity after experimental aspergillosis. ELECTROPHORESIS, 31(12): 1947-58.
  3. Bramlage CP, Armstrong VW, Zapf A, Bramlage P, Mueller GA, Koziolek MJ (2010) Low-density lipoprotein apheresis decreases ferritin, transferrin and vitamin B12, which may cause anemia in serially treated patients. THER APHER DIAL, 14(2): 136-42.
  4. Brandhorst G, Brehmer F, Petrova DT, Gross O, Miosge N, Armstrong VW, Oellerich M (2010) Mycophenolic acid predose concentrations and renal function in a mouse model for progressive renal fibrosis. THER DRUG MONIT, 32(1): 73-8.
  5. Edelmann F, Schmidt AG, Gelbrich G, Binder L, Herrmann-Lingen C, Halle M, Hasenfuss G, Wachter R, Pieske B (2010) Rationale and design of the 'aldosterone receptor blockade in diastolic heart failure' trial: a double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function in patients with symptomatic diastolic heart failure (Aldo-DHF). EUR J HEART FAIL, 12(8): 874-82.
  6. Feichtiger H, Wieland E, Armstrong VW, Shipkova M (2010) The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro. Clin Biochem, 43(1-2): 208-13.
  7. Gawinecka J, Dieks J, Asif AR, Carimalo J, Heinemann U, Streich JH, Dihazi H, Schulz-Schaeffer W, Zerr I (2010) Codon 129 polymorphism specific cerebrospinal fluid proteome pattern in sporadic Creutzfeldt-Jakob disease and the implication of glycolytic enzymes in prion-induced pathology. J PROTEOME RES, 9(11): 5646-57.
  8. Knöferle J, Ramljak S, Koch JC, Tönges L, Asif AR, Michel U, Wouters FS, Heermann S, Krieglstein K, Zerr I, Bähr M, Lingor P (2010) TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP. Neurobiol Dis (Internet-Ausgabe), 38(3): 395-404.
  9. Koziolek MJ, Hennig U, Zapf A, Bramlage C, Grupp C, Armstrong VW, Strutz F, Müller GA (2010) Retrospective analysis of long-term lipid apheresis at a single center. THER APHER DIAL, 14(2): 143-52.
  10. Lüers C, Schmidt A, Wachter R, Fritzsche F, Sutcliffe A, Kleta S, Zapf A, Hagenah G, Binder L, Maisch B, Pieske B (2010) Serial NT-proBNP measurements for risk stratification of patients with decompensated heart failure. Herz (Internet-Ausgabe), 35(7): 488-95.
  11. Luers C, Wachter R, Kleta S, Uhlir M, Koschack J, Scherer M, Binder L, Herrmann-Lingen C, Zapf A, Kulle B, Kochen MM, Pieske B (2010) Natriuretic peptides in the detection of preclinical diastolic or systolic dysfunction. Clin Res Cardiol (Internet-Ausgabe), -: -.
  12. Lüers C, Hagenah G, Wachter R, Kleta S, Schaumberg J, Riedel S, Binder L, Jung K, Schmidt A, Pieske B (2010) [Importance of surfactant proteins B and D for the differential diagnosis of acute dyspnea]. Med Klin (Munich), 105(9): 611-8.
  13. Meyer T, Stanske B, Kochen MM, Cordes A, Yüksel I, Wachter R, Lüers C, Scherer M, Binder L, Pieske B, Herrmann-Lingen C (2010) Elevated serum levels of interleukin-10 and tumor necrosis factor are both associated with vital exhaustion in patients with cardiovascular risk factors. PSYCHOSOMATICS, 51(3): 248-56.
  14. Petrova DT, Brandhorst G, Brehmer F, Gross O, Oellerich M, Armstrong VW (2010) Mycophenolic acid displays IMPDH-dependent and IMPDH-independent effects on renal fibroblast proliferation and function. THER DRUG MONIT, 32(4): 405-12.
  15. Schmidt C, Redyk K, Meissner B, Krack L, von Ahsen N, Roeber S, Kretzschmar H, Zerr I (2010) Clinical features of rapidly progressive Alzheimer's disease. Dement Geriatr Cogn (Internet-Ausgabe), 29(4): 371-8.
  16. Schott P, Jacobshagen C, Köhler J, Seidler T, Asif AR, Dihazi H, Hasenfuss G, Maier LS (2010) Proteome changes in CaMKIIdelta(C)-overexpressing cardiac myocytes. Cardiovasc Pathol, im Druck: im Druck.
  17. Schultze FC, Petrova DT, Oellerich M, Armstrong VW, Asif AR (2010) Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus. Cell Proliferat (Internet-Ausgabe), 43(4): 396-404.
  18. Singh B, Oellerich M, Kumar R, Kumar M, Bhadoria DP, Reichard U, Gupta VK, Sharma GL, Asif AR (2010) Immuno-reactive molecules identified from the secreted proteome of Aspergillus fumigatus. J PROTEOME RES, 9(11): 5517-29.
  19. Singh B, Sharma GL, Oellerich M, Kumar R, Singh S, Bhadoria DP, Katyal A, Reichard U, Asif AR (2010) Novel cytosolic allergens of Aspergillus fumigatus identified from germinating conidia. J PROTEOME RES, 9(11): 5530-41.
  20. Soldin SJ, Hardy RW, Wians FH, Balko JA, Mendu DR, Chaffin CH, Streit F, Barbarakis M, Martel J, Canfield W, Levy HR, Oellerich M (2010) Performance evaluation of the new ADVIA Centaur system cyclosporine assay (single-step extraction). CLIN CHIM ACTA, 411(11-12): 806-11.
  21. Stahrenberg R, Edelmann F, Mende M, Kockskämper A, Düngen HD, Scherer M, Kochen MM, Binder L, Herrmann-Lingen C, Gelbrich G, Hasenfuß G, Pieske B, Wachter R (2010) Association of glucose metabolism with diastolic function along the diabetic continuum. DIABETOLOGIA, [Epub ahead of print]: [Epub ahead of print].
  22. Stahrenberg R, Edelmann F, Mende M, Kockskämper A, Düngen HD, Lüers C, Binder L, Herrmann-Lingen C, Gelbrich G, Hasenfuß G, Pieske B, Wachter R (2010) The novel biomarker growth differentiation factor 15 in heart failure with normal ejection fraction. EUR J HEART FAIL, 12(12): 1309-1316.
  23. Weiss E, Ramljak S, Asif AR, Ciesielczyk B, Schmitz M, Gawinecka J, Schulz-Schaeffer W, Behrens C, Zerr I (2010) Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study. Neuroscience (Internet-Ausgabe), 169(4): 1640-50.
  24. Wieland E, Olbricht CJ, Süsal C, Gurragchaa P, Böhler T, Israeli M, Sommerer C, Budde K, Hartmann B, Shipkova M, Oellerich M (2010) Biomarkers as a tool for management of immunosuppression in transplant patients. THER DRUG MONIT, 32(5): 560-72.

 Medizinische Dissertationen

  1. Blanckenberg A, Dr. med., Maximaltherapie der Hypercholesterolämie: LDL-Apherese und unterschiedliche Kombinationen von Statinen. Dissertation Universität Göttingen 2010.

 

 

Publikationen 2009

 Journalbeiträge

 

  1. Armstrong (2009) Thirty years of therapeutic drug monitoring. THER DRUG MONIT, 31(6): 669.
  2. Arzideh F, Brandhorst G, Gurr E, Hinsch W, Hoff T, Roggenbuck L, Rothe G, Schumann G, Wolters B, Wosniok W, Haeckel R (2009) An improved indirect approach for determining reference limits from intra-laboratory data bases exemplified by concentrations of electrolytes. Laboratoriumsmedizin, 33 (2): 52-66.
  3. Asif AR, Hecker M, Cattaruzza M (2009) Disinhibition of SOD-2 expression to compensate for a genetically determined NO deficit in endothelial cells--brief report. Arterioscl Throm Vas (Internet-Ausgabe), 29(11): 1890-3.
  4. Asif AR, Oellerich M, Armstrong VW, Hecker M, Cattaruzza M (2009) T-786C polymorphism of the NOS-3 gene and the endothelial cell response to fluid shear stress-a proteome analysis. J PROTEOME RES, 8(6): 3161-3168.
  5. Atanasova S, Wieland E, Schlumbohm C, Korecka M, Shaw L, von Ahsen N, Fuchs E, Oellerich M, Armstrong V (2009) Prenatal dexamethasone exposure in the common marmoset monkey enhances gene expression of antioxidant enzymes in the aorta of adult offspring. STRESS, 12(3): 215-24.
  6. Beckebaum S, Armstrong VW, Cicinnati VR, Streit F, Klein CG, Gerken G, Paul A, Oellerich M (2009) Pharmacokinetics of mycophenolic acid and its glucuronide metabolites in stable adult liver transplant recipients with renal dysfunction on a low-dose calcineurin inhibitor regimen and mycophenolate mofetil. THER DRUG MONIT, 31(2): 205-10.
  7. Bramlage CP, Schlumbohm C, Pryce CR, Mirza S, Schnell C, Amann K, Amstrong VW, Eitner F, Zapf A, Feldon J, Oellerich M, Fuchs E, Müller GA, Strutz F (2009) Prenatal dexamethasone exposure does not alter blood pressure and nephron number in the young adult marmoset monkey. Hypertension (Internet-Ausgabe), 54(5): 1115-22.
  8. Brandhorst G, Luthe H, Domke I, Knoke C, Rhode KH, Sauter H, Oellerich M (2009) Therapeutic drug monitoring and drugs of abuse testing on the cobas 6000 analyzer series: analytical performance under routine-like conditions. CLIN CHEM LAB MED, 47(7): 854-9.
  9. Braun F, Schöcklmann H, Ziegler E, Kunzendorf U, Armstrong VW, Renders L (2009) Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics. Clin Pharmacol Ther (Internet-Ausgabe), 86(4): 411-5.
  10. Cotte S, von Ahsen N, Kruse N, Huber B, Winkelmann A, Zettl UK, Starck M, König N, Tellez N, Dörr J, Paul F, Zipp F, Lühder F, Koepsell H, Pannek H, Montalban X, Gold R, Chan A (2009) ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. Brain (Internet-Ausgabe), 132(Pt 9): 2517-30.
  11. Dörr J, Bitsch A, Schmailzl KJG, Chan A, von Ahsen N, Hummel M, Varon R, Lill CM, Vogel HP, Zipp F, Paul F (2009) Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment. Neurology (Internet-Ausgabe), 73(12): 991-3.
  12. Guerchet M, Houinato D, Paraiso MN, von Ahsen N, Nubukpo P, Otto M, Clément JP, Preux PM, Dartigues JF (2009) Cognitive Impairment and Dementia in Elderly People Living in Rural Benin, West Africa. DEMENT GERIATR COGN, 27(1): 34-41.
  13. Heller T, Asif AR, Petrova DT, Doncheva Y, Wieland E, Oellerich M, Shipkova M, Armstrong VW (2009) Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho GDP dissociation inhibitor 2. THER DRUG MONIT, 31(2): 211-7.
  14. Krasnianski A, von Ahsen N, Heinemann U, Meissner B, Schulz-Schaeffer WJ, Kretzschmar HA, Armstrong VW, Zerr I (2009) Increased frequency of positive family history of dementia in sporadic CJD. NEUROBIOL AGING, 30(4): 615-21.
  15. Linker RA, Brechlin P, Jesse S, Steinacker P, Lee DH, Asif AR, Jahn O, Tumani H, Gold R, Otto M (2009) Proteome profiling in murine models of multiple sclerosis: identification of stage specific markers and culprits for tissue damage. PLoS One, 4(10): e7624.
  16. Norozi K, Binder L, Brack C, Potthoff L, Hess G, Wessel A (2009) Intravenous luteinizing hormone-releasing hormone has no effect on serum N-terminal pro-brain natriuretic peptide in children and adolescents. PEDIATR INT, 51(2): 283-8.
  17. Nyirenda MJ, Carter R, Tang JI, de Vries A, Schlumbohm C, Hillier SG, Streit F, Oellerich M, Armstrong VW, Fuchs E, Seckl JR (2009) Prenatal programming of metabolic syndrome in the common marmoset is associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1. Diabetes (Internet-Ausgabe), 58(12): 2873-9.
  18. Pal A, Kraetzner R, Gruene T, Grapp M, Schreiber K, Grønborg M, Urlaub H, Becker S, Asif AR, Gärtner J, Sheldrick GM, Steinfeld R (2009) Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis. J BIOL CHEM, 284(6): 3976-84.
  19. Petrova DT, Heller T, Hitt R, Wieland E, Oellerich M, Armstrong VW, Shipkova M (2009) Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition. THER DRUG MONIT, 31(1): 31-41.
  20. Schütz E, von Ahsen N (2009) Influencing factors of dsDNA dye (high-resolution) melting curves and improved genotype call based on thermodynamic considerations. ANAL BIOCHEM, 385(1): 143-52.
  21. van Gelder T, Domke I, Engelmayer J, de Fijter H, Kuypers D, Budde K, Koeger R, Luthe H, Oellerich M (2009) Clinical utility of a new enzymatic assay for determination of mycophenolic acid in comparison with an optimized LC-MS/MS method. THER DRUG MONIT, 31(2): 218-23.
  22. von Ahsen N, Binder C, Brockmöller J, Oellerich M (2009) CYP2D6 und Tamoxifen: pharmakogenetische Neuentdeckung eines etablierten Medikaments? Laboratoriumsmedizin, 33 (5): 293-302.
  23. Vorwerk CK, Tuchen S, Streit F, Binder L, Hofmüller W, Behrens-Baumann W (2009) Aqueous humor concentrations of topically administered caspofungin in rabbits. Ophthal Res (Internet-Ausgabe), 41(2): 102-5.
  24. Wallemacq P, Armstrong VW, Brunet M, Haufroid V, Holt DW, Johnston A, Kuypers D, Le Meur Y, Marquet P, Oellerich M, Thervet E, Toenshoff B, Undre N, Weber LT, Westley IS, Mourad M (2009) Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. THER DRUG MONIT, 31(2): 139-52.
  25. Zibat A, Uhmann A, Nitzki F, Wijgerde M, Frommhold A, Heller T, Armstrong V, Wojnowski L, Quintanilla-Martinez L, Reifenberger J, Schulz-Schaeffer W, Hahn H (2009) Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts. Carcinogenesis (Internet-Ausgabe), 30(6): 918-26.

 Medizinische Dissertationen

 

  1. Bothur-Schäfer P, Dr. med., Evaluation von a- und µ-Gluttathion-S-Transferase als Marker des intestinalen Ischämie-Reperfusionsschadens am Modell der extrakorporalen Dünndarmperfusion beim Schwein. Dissertation Universität Göttingen 2009.

 

 

Publikationen 2008

 Journalbeiträge

 

  1. Bachmann CG, Guth N, Helmschmied K, Armstrong VW, Paulus W, Happe S (2008) Homocysteine in restless legs syndrome. SLEEP MED, 9(4): 388-92.
  2. Brandhorst G, Marquet P, Shaw LM, Liebisch G, Schmitz G, Coffing MJ, Domke I, Streit F, Luthe H, Oellerich M (2008) Multicenter evaluation of a new inosine monophosphate dehydrogenase inhibition assay for quantification of total mycophenolic acid in plasma. THER DRUG MONIT, 30(4): 428-33.
  3. Brandhorst G, Tenderich G, Zittermann A, Oezpeker C, Koerfer R, Oellerich M, Armstrong VW (2008) Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor. THER DRUG MONIT, 30(1): 113-116.
  4. Chan A, Stüve O, von Ahsen N (2008) Immunosuppression in clinical practice: approaches to individualized therapy. J NEUROL, 255 Suppl 6: 22-7.
  5. Heller T, Geide A, Bonitz U, Wegner U, Gröne HJ, Armstrong VW, Oellerich M (2008) Effect of the antioxidant idebenone on adverse events under mycophenolate mofetil therapy in a rat model. TRANSPLANTATION, 85(5): 739-47.
  6. Heller T, Nagel I, Ehrlich B, Bähr M, Strik H (2008) Automated cerebrospinal fluid cytology. ANAL QUANT CYTOL, 30(3): 139-44.
  7. Koschack J, Scherer M, Lüers C, Kochen MM, Wetzel D, Kleta S, Pouwels C, Wachter R, Herrmann-Lingen C, Pieske B, Binder L (2008) Natriuretic peptide vs. clinical information for diagnosis of left ventricular systolic dysfunction in primary care. BMC Fam Pract, 9: 14.
  8. Krasnianski A, von Ahsen N, Heinemann U, Meissner B, Kretzschmar HA, Armstrong VW, Zerr I (2008) ApoE distribution and family history in genetic prion diseases in Germany. J MOL NEUROSCI, 34(1): 45-50.
  9. Lorf T, Schnitzbauer AA, Schaefers SK, Scherer MN, Schlitt HJ, Oellerich M, Becker H, Obed A (2008) Prognostic value of the monoethylglycinexylidide (MEGX)-test prior to liver resection. HEPATO-GASTROENTEROL, 55(82-83): 539-43.
  10. Mocarelli P, Horowitz GL, Gerthoux PM, Cecere R, Imdahl R, Ruinemans-Koerts J, Luthe H, Calatayud SP, Salve ML, Kunst A, McGovern M, Ng K, Stockmann W (2008) Increasing Efficiency and Quality by Consolidation of Clinical Chemistry and Immunochemistry Systems with MODULAR ANALYTICS SWA. J AUTOM METHOD MANAG, 2008: 498921.
  11. Müller A, Eis-Hübinger AM, Brandhorst G, Heep A, Bartmann P, Franz AR (2008) Oral valganciclovir for symptomatic congenital cytomegalovirus infection in an extremely low birth weight infant. J Perinatol, 28(1): 74-6.
  12. Petrova DT, Asif Abdul R, Armstrong Victor W, Dimova I, Toshev S, Yaramov N, Oellerich M, Toncheva D (2008) Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer. CLIN BIOCHEM, 41(14-15): 1224-36.
  13. Petrova DT, Nedeva P, Maslyankov S, Toshev S, Yaramov N, Atanasova S, Toncheva D, Oellerich M, von Ahsen N (2008) No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients. J CANCER RES CLIN, 134(3): 317-22.
  14. Ramljak S, Asif AR, Armstrong VW, Wrede A, Groschup MH, Buschmann A, Schulz-Schaeffer W, Bodemer W, Zerr I (2008) Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems. J PROTEOME RES, 7(7): 2681-95.
  15. Roedl JB, Bleich S, Schlötzer-Schrehardt U, von Ahsen N, Kornhuber J, Naumann GOH, Kruse FE, Jünemann AGM (2008) Increased homocysteine levels in tear fluid of patients with primary open-angle glaucoma. OPHTHAL RES, 40(5): 249-56.
  16. Samoylenko A, Byts N, Rajalingam K, von Ahsen N, Rapp UR, Ehrenreich H, Sirén AL (2008) Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK signalling. CELL SIGNAL, 20(1): 154-62.
  17. Schott P, Asif AR, Gräf C, Toischer K, Hasenfuss G, Kögler H (2008) Myocardial adaptation of energy metabolism to elevated preload depends on calcineurin activity : a proteomic approach. BASIC RES CARDIOL, 103(3): 232-43.
  18. van Agteren M, Armstrong VW, van Schaik RH, de Fijter H, Hartmann A, Zeier M, Budde K, Kuypers D, Pisarski P, Le Meur Y, van der Werf M, Mamelok RD, Oellerich M, van Gelder T (2008) AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism. THER DRUG MONIT, 30(4): 439-44.
  19. van Gelder T, Silva HT, de Fijter JW, Budde K, Kuypers D, Tyden G, Lohmus A, Sommerer C, Hartmann A, Le Meur Y, Oellerich M, Holt DW, Tönshoff B, Keown P, Campbell S, Mamelok RD (2008) Comparing mycophenolate mofetil regimens for de novo renal transplant recipients: the fixed-dose concentration-controlled trial. TRANSPLANTATION, 86(8): 1043-51.
  20. von Ahsen N, Oellerich M, Armstrong VW (2008) Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotype-phenotype correlation and promoter function. THER DRUG MONIT, 30(1): 16-22.
  21. Vorwerk CK, Streit F, Binder L, Tuchen S, Knop C, Behrens-Baumann W (2008) Aqueous humor concentration of voriconazole after topical administration in rabbits. GRAEF ARCH CLIN EXP, 246(8): 1179-83.
  22. Weber L, Hoecker B, Armstrong V, Oellerich M, Tönshoff B (2008) Long-Term Pharmacokinetics of Mycophenolic Acid in Pediatric Renal Transplant Recipients Over 3 Years Posttransplant. THER DRUG MONIT, 30(5): 570-5.
  23. Wilhelm J, Frieling H, von Ahsen N, Hillemacher T, Kornhuber J, Bleich S (2008) Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction. PHARMACOGENOMICS J, 8(2): 17-21.

 

 

Publikationen 2007

 Journalbeiträge

 

  1. Agarwal RP, Peters SM, Shemirani M, von Ahsen N (2007) Improved real-time multiplex polymerase chain reaction detection of methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms using nearest neighbor model-based probe design. J MOL DIAGN, 9(3): 345-50.
  2. Asif AR, Armstrong VW, Voland A, Wieland E, Oellerich M, Shipkova M (2007) Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats. BIOCHIMIE, 89(3): 393-402.
  3. Atanasova S, Shipkova M, Svinarov D, Mladenova A, Genova M, Wieland E, Oellerich M, von Ahsen N (2007) Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6. THER DRUG MONIT, 29(1): 6-10.
  4. Bachmann CG, Guth N, Helmschmied K, Armstrong VW, Paulus W, Happe S (2007) Homocysteine in restless legs syndrome. SLEEP MED, Sep 25 [Epub ahead of print].
  5. Datson NA, Morsink MC, Atanasova S, Armstrong VW, Zischler H, Schlumbohm C, Dutilh BE, Huynen MA, Waegele B, Ruepp A, de Kloet ER, Fuchs E (2007) Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate. BMC GENOMICS, 8: 190.
  6. Davies NM, Grinyó J, Heading R, Maes B, Meier-Kriesche HU, Oellerich M (2007) Gastrointestinal side effects of mycophenolic acid in renal transplant patients: a reappraisal. NEPHROL DIAL TRANSPL, 22(9): 2440-8.
  7. Dihazi H, Müller GA, Lindner S, Meyer M, Asif AR, Oellerich M, Strutz F (2007) Characterization of diabetic nephropathy by urinary proteomic analysis: identification of a processed ubiquitin form as a differentially excreted protein in diabetic nephropathy patients. CLIN CHEM, 53(9): 1636-45.
  8. Dresing K, Armstrong VW, Leip CL, Streit F, Burchardi H, Stürmer KM, Oellerich M (2007) Real-time assessment of hepatic function is related to clinical outcome in critically ill patients after polytrauma. CLIN BIOCHEM, 40(16-17): 1194-1200.
  9. Heller T, van Gelder T, Budde K, de Fijter JW, Kuypers D, Arns W, Schmidt J, Rostaing L, Powis SH, Claesson K, Macphee IA, Pohanka E, Engelmayer J, Brandhorst G, Oellerich M, Armstrong VW (2007) Plasma concentrations of mycophenolic Acid acyl glucuronide are not associated with diarrhea in renal transplant recipients. AM J TRANSPLANT, 7:1822-3.
  10. Krasnianski A, von Ahsen N, Heinemann U, Meissner B, Schulz-Schaeffer WJ, Kretzschmar HA, Armstrong VW, Zerr I (2007) Increased frequency of positive family history of dementia in sporadic CJD. Neurobiol Aging, Sep 24 [Epub ahead of print].
  11. Norozi K, Wessel A, Alpers V, Arnhold JO, Binder L, Geyer S, Zoege M, Buchhorn R (2007) Chronotropic incompetence in adolescents and adults with congenital heart disease after cardiac surgery. J CARD FAIL, 13(4): 263-8.
  12. Petrova DT, Nedeva P, Maslyankov S, Toshev S, Yaramov N, Atanasova S, Toncheva D, Oellerich M, von Ahsen N (2007) No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients. J CANCER RES CLIN, Aug 3 [Epub ahead of print].
  13. Petrova DT, Yaramov N, Toshev S, Nedeva P, Maslyankov S, von Ahsen N, Oellerich M, Toncheva D (2007) Genotyping of CYP3A5 polymorphisms among Bulgarian patients with sporadic colorectal cancer and controls. ONCOLOGIST, 30(11): 559-63.
  14. Puls M, Dellas C, Lankeit M, Olschewski M, Binder L, Geibel A, Reiner C, Schäfer K, Hasenfuss G, Konstantinides S (2007) Heart-type fatty acid-binding protein permits early risk stratification of pulmonary embolism. EUR HEART J, 28(2): 224-9.
  15. Reinshagen M, Schutz Dagger E, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Kruis W, Oellerich M, von Ahsen N (2007) 6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial. CLIN CHEM, 53:1306-14.
  16. Roedl JB, Bleich S, Reulbach U, von Ahsen N, Schlötzer-Schrehardt U, Rejdak R, Naumann GO, Kruse FE, Kornhuber J, Jünemann AG (2007) Homocysteine levels in aqueous humor and plasma of patients with primary open-angle glaucoma. J NEURAL TRANSM, 114(4): 445-50.
  17. Uhmann A, Dittmann K, Nitzki F, Dressel R, Koleva M, Frommhold A, Zibat A, Binder C, Adham I, Nitsche M, Heller T, Armstrong V, Schulz-Schaeffer W, Wienands J, Hahn H (2007) The Hedgehog receptor Patched controls lymphoid lineage commitment. BLOOD, 110:1814-23.
  18. van Hest RM, Doorduijn JK, de Winter BC, Cornelissen JJ, Vulto AG, Oellerich M, Löwenberg B, Mathot RA, Armstrong VW, van Gelder T (2007) Pharmacokinetics of mycophenolate mofetil in hematopoietic stem cell transplant recipients. THER DRUG MONIT, 29(3): 353-360.
  19. von Ahsen N, Oellerich M (2007) Chip-based genotyping: translation of pharmacogenetic research to clinical practice. CLIN CHEM, 53(7): 1186-7.
  20. Wachter R, Lüers C, Kleta S, Griebel K, Herrmann-Lingen C, Binder L, Janicke N, Wetzel D, Kochen MM, Pieske B (2007) Impact of diabetes on left ventricular diastolic function in patients with arterial hypertension. EUR J HEART FAIL, 9(5): 469-76.
  21. Wilhelm J, Frieling H, von Ahsen N, Hillemacher T, Kornhuber J, Bleich S (2007) Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction. PHARMACOGENOMICS J, Apr 10 [Epub ahead of print].
  22. Wilhelm J, von Ahsen N, Hillemacher T, Bayerlein K, Frieling H, Kornhuber J, Bleich S (2007) Apolipoprotein E gene polymorphism and previous alcohol withdrawal seizures. J PSYCHIATR RES, 41(10): 871-5.
  23. Wolff NA, Burckhardt BC, Burckhardt G, Oellerich M, Armstrong VW (2007) Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney. NEPHROL DIAL TRANSPL, 22:2497-503.

 

 

Publikationen 2006

 Journalbeiträge

 

  1. Asif AR, Ljubojevic M, Sabolic I, Shnitsar V, Metten M, Anzai N, Mueller GA, Burckhardt G, Hagos Y (2006) Regulation of steroid hormone biosynthesis enzymes and organic anion transporters by forskolin and DHEA-S treatment in adrenocortical cells. AM J PHYSIOL-ENDOC M, -: -.´
  2. Asif AR, Oellerich M, Amstrong VW, Riemenschneider B, Monod M, Reichard U (2006) Proteome of conidial surface associated proteins of Aspergillus fumigatus reflecting potential vaccine candidates and allergens. J PROTEOME RES, 5(4): 954-62.
  3. Atanasova S, von Ahsen N, Schlumbohm C, Wieland E, Oellerich M, Armstrong V (2006) Marmoset glutathione peroxidases: cDNA sequences, molecular evolution, and gene expression. J MED PRIMATOL, 35(3): 155-64.
  4. Bazarian JJ, Beck C, Blyth B, von Ahsen N, Hasselblatt M (2006) Impact of creatine kinase correction on the predictive value of S-100B after mild traumatic brain injury. RESTOR NEUROL NEUROS, 24(3): 163-72.
  5. Birnbaum F, Reis A, Böhringer D, Sokolowska Y, Mayer K, Voiculescu A, Oellerich M, Sundmacher R, Reinhard T (2006) An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty. TRANSPLANTATION, 81(5): 767-72.
  6. Brandhorst G, Streit F, Goetze S, Oellerich M, Armstrong VW (2006) Quantification by liquid chromatography tandem mass spectrometry of mycophenolic acid and its phenol and acyl glucuronide metabolites. CLIN CHEM, 52(10): 1962-4.
  7. Hasselblatt M, Krampe H, Jacobs S, Sindram H, Armstrong VW, Hecker M, Ehrenreich H (2006) Arginine challenge unravels persistent disturbances of urea cycle and gluconeogenesis in abstinent alcoholics. ALCOHOL ALCOHOLISM, 41(4): 372-8.
  8. Held T, Paprotta I, Khulan J, Hemmerlein B, Binder L, Wolf S, Schubert S, Meinhardt A, Engel W, Adham IM (2006) Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development. MOL CELL BIOL, 26(21): 8099-108.
  9. Heller T, Kirchheiner J, Armstrong VW, Luthe H, Tzvetkov M, Brockmöller J, Oellerich M (2006) AmpliChip CYP450 GeneChip(R): A New Gene Chip That allows Rapid and Accurate CYP2D6 Genotyping. THER DRUG MONIT, 28(5): 673-677.
  10. Hillemacher T, Wilhelm J, von Ahsen N, Bayerlein K, Frieling H, Kornhuber J, Bleich S (2006) Obsessive-compulsive alcohol craving is not associated with Apolipoprotein E genotype. PSYCHIAT GENET, 16(6): 231-2.
  11. Koehler SC, Ahsen NV, Schlumbohm C, Asif AR, Goedtel-Armbrust U, Oellerich M, Wojnowski L, Armstrong VW (2006) Marmoset CYP3A21, a model for human CYP3A4: protein expression and functional characterization of the promoter.
  12. Michalsen A, Knoblauch NT, Lehmann N, Grossman P, Kerkhoff G, Wilhelm FH, Moebus S, Konstantinides S, Binder L, Heusch G, Siffert W, Budde T, Dobos GJ (2006) Effects of lifestyle modification on the progression of coronary atherosclerosis, autonomic function, and angina--the role of GNB3 C825T polymorphism. AM HEART J, 151(4): 870-7.
  13. Mollenhauer B, Trenkwalder C, von Ahsen N, Bibl M, Steinacker P, Brechlin P, Schindehuette J, Poser S, Wiltfang J, Otto M (2006) Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson's disease dementia. DEMENT GERIATR COGN, 22(3): 200-8.
  14. Naesens M, Kuypers DR, Streit F, Armstrong VW, Oellerich M, Verbeke K, Vanrenterghem Y (2006) Rifampin induces alterations in mycophenolic acid glucuronidation and elimination: implications for drug exposure in renal allograft recipients. CLIN PHARMACOL THER, 80(5): 509-21.
  15. Norozi K, Buchhorn R, Bartmus D, Alpers V, Arnhold JO, Schoof S, Zoege M, Binder L, Geyer S, Wessel A (2006) Elevated brain natriuretic peptide and reduced exercise capacity in adult patients operated on for tetralogy of fallot is due to biventricular dysfunction as determined by the myocardial performance index. AM J CARDIOL, 97(9): 1377-82.
  16. Oellerich M, Armstrong VW (2006) The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments. THER DRUG MONIT, 28(6): 720-5.
  17. Oellerich M, Barten MJ, Armstrong VW (2006) Biomarkers: the link between therapeutic drug monitoring and pharmacodynamics. THER DRUG MONIT, 28(1): 35-8.
  18. Reichard U, Léchenne B, Asif AR, Streit F, Grouzmann E, Jousson O, Monod M (2006) Sedolisins, a new class of secreted proteases from Aspergillus fumigatus with endoprotease or tripeptidyl-peptidase activity at acidic pHs. APPL ENVIRON MICROB, 72(3): 1739-48.
  19. Rölleke U, Flügge G, Plehm S, Schlumbohm C, Armstrong VW, Dressel R, Uchanska-Ziegler B, Ziegler A, Fuchs E, Czéh B, Walter L (2006) Differential expression of major histocompatibility complex class I molecules in the brain of a New World monkey, the common marmoset (Callithrix jacchus). J NEUROIMMUNOL, 176(1-2): 39-50.
  20. Schuttrumpf S, Binder L, Hagemann T, Berkovic D, Trumper L, Binder C (2006) Utility of procalcitonin concentration in the evaluation of patients with malignant diseases and elevated C-reactive protein plasma concentrations. CLIN INFECT DIS, 43(4): 468-73.
  21. Shipkova M, Lorenz K, Oellerich M, Wieland E, von Ahsen N (2006) Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a Caucasian population. CLIN CHEM, 52(2): 240-7.
  22. Stefanovic V, Toncheva D, Atanasova S, Polenakovic M (2006) Etiology of Balkan endemic nephropathy and associated urothelial cancer. AM J NEPHROL, 26(1): 1-11.
  23. Then Bergh F, Niklas A, Strauss A, von Ahsen N, Niederwieser D, Schwarz J, Wagner A, Al-Ali HK (2006) Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis. ACTA HAEMATOL-BASEL, 116(3): 207-10.
  24. Weber LT, Hoecker B, Armstrong VW, Oellerich M, Tönshoff B (2006) Validation of an abbreviated pharmacokinetic profile for the estimation of mycophenolic acid exposure in pediatric renal transplant recipients. THER DRUG MONIT, 28(5): 623-631.
  25. Wilson D, Johnston F, Holt D, Moreton M, Engelmayer J, Gaulier JM, Luthe H, Marquet P, Moscato D, Oellerich M, Mosso R, Streit F, Brunet M, Fillee C, Schmid R, Wallemacq P, Barnes G (2006) Multi-center evaluation of analytical performance of the microparticle enzyme immunoassay for sirolimus. CLIN BIOCHEM, -: -.
  26. van Gelder T, Le Meur Y, Shaw LM, Oellerich M, DeNofrio D, Holt C, Holt DW, Kaplan B, Kuypers D, Meiser B, Toenshoff B, Mamelok RD (2006) Therapeutic drug monitoring of mycophenolate mofetil in transplantation. THER DRUG MONIT, 28(2): 145-54.

 Medizinische Dissertationen

 

  1. Voland A, Dr. med., Untersuchung zur Bedeutung des Acylglukuronids der Mycophenolsäure für gastrointestinale Nebenwirkungen unter der Therapie mit Mycophenolatmofetil. Dissertation Universität Göttingen 2006.

 

 

Publikationen 2005

 Journalbeiträge

 

  1. Armstrong VW, Tenderich G, Shipkova M, Parsa A, Koerfer R, Schröder H, Oellerich M. Pharmacokinetics and bioavailability of mycophenolic acid after intravenous administration and oral administration of mycophenolate mofetil to heart transplant recipients. Ther Drug Monit 2005; 27: 315-321.
  2. Asif AR, Steffgen J, Metten M, Grunewald RW, Müller GA, Bahn A, Burckhardt G, Hagos Y. Presence of organic anion transporters 3 (OAT3) and 4 (OAT4) in human adrenocortical cells. Pflug Arch Eur J Phy 2005; 450: 88-95.
  3. Atanasova SY, von Ahsen N, Toncheva DI, Dimitrov TG, Oellerich M, Armstrong VW. Genetic polymorphisms of cytochrome P450 among patients with Balkan endemic nephropathy (BEN). Clin Biochem 2005; 38: 223-8.
  4. Barten MJ, Shipkova M, Bartsch P, Dhein S, Streit F, Tarnok A, Armstrong VW, Mohr FW, Oellerich M, Gummert JF. Mycophenolic acid interaction with cyclosporine and tacrolimus in vitro and in vivo: evaluation of additive effects on rat blood lymphocyte function. Ther Drug Monit 2005; 27: 123-31.
  5. Binder L, Pieske B, Olschewski M, Geibel A, Klostermann B, Reiner C, Konstantinides S. N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation 2005; 112: 1573-9.
  6. Dihazi H, Rahman AA, Agarwal NK, Doncheva Y, Müller GA. Proteomics analysis of cellular response to osmotic stress in TALH-cells. Mol Cell Proteomics2005; 4: 1445-8.
  7. Ehrenreich H, Hasselblatt M, Knerlich F, von Ahsen N, Jacob S, Sperling S, Woldt H, Vehmeyer K, Nave KA, Sirén AL. A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain. P Natl Acad Sci USA 2005; 102: 862-7.
  8. El Desoky ES, Abdelsalam YM, Salama RH, El Akkad MA, Atanasova S, von Ahsen N, Armstrong VW, Oellerich M. NAT2*5/*5 genotype (341T>C) is a potential risk factor for schistosomiasis-associated bladder cancer in Egyptians. Ther Drug Monit 2005; 27: 297-304.
  9. Hagemann T, Binder C, Binder L, Pukrop T, Trümper L, Grimshaw MJ. Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells. DNA Cell Biol 2005; 24: 766-76.
  10. Heyer A, Hasselblatt M, von Ahsen N, Häfner H, Sirén AL, Ehrenreich H. In vitro gender differences in neuronal survival on hypoxia and in 17beta-estradiol-mediated neuroprotection. J Cerebr Blood F Met 2005; 25: 427-30.
  11. Jünemann AG, von Ahsen N, Reulbach U, Roedl J, Bönsch D, Kornhuber J, Kruse FE, Bleich S. C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma. Am J Ophthalmol 2005; 139: 721-3.
  12. Kamdem LK, Streit F, Zanger UM, Brockmöller J, Oellerich M, Armstrong VW, Wojnowski L. Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus. Clin Chem; 51: 1374-81.
  13. Langenbeck U, Baum F, Mench-Hoinowski A, Luthe H, Behbehani AW. Predicting the phenylalanine blood concentration from urine analyses. An approach to noninvasive monitoring of patients with phenylketonuria. J Inherit Metab Dis 2005; 28: 855-61.
  14. Meier-Kriesche HU, Davies NM, Grinyó J, Heading R, Mamelok R, Wijngaard P, Oellerich M, Maes B. Mycophenolate sodium does not reduce the incidence of GI adverse events compared with mycophenolate mofetil. Am J Transplant 2005; 5: 1164; author reply 1165-6.
  15. Mielck F, Ziarkowski A, Hanekop G, Armstrong VW, Hilgers R, Weyland A, Quintel M, Sonntag H. Cerebral inflammatory response during and after cardiac surgery. Eur J Anaesth 2005 ; 22: 347-52.
  16. Norozi K, Buchhorn R, Kaiser C, Hess G, Grunewald RW, Binder L, Wessel A. Plasma N-terminal pro-brain natriuretic peptide as a marker of right ventricular dysfunction in patients with tetralogy of Fallot after surgical repair. Chest 2005; 128: 2563-70.
  17. Saur P, Niedmann PD, Brunner E, Kettler D. Do intracellular, extracellular or urinary magnesium concentrations predict renal retention of magnesium in critically ill patients? Eur J Anaesth 2005 ; 22: 148-53.
  18. Strik H, Luthe H, Nagel I, Ehrlich B, Bahr M. Automated cerebrospinal fluid cytology: limitations and reasonable applications. Anal Quant Cytol 2005 ; 27: 167-73.
  19. von Ahsen N. Two for typing: homogeneous combined single-nucleotide polymorphism scanning and genotyping. Clin Chem 2005; 51: 1761-2.
  20. von Ahsen N, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Oellerich M, Kruis W, Reinshagen M. Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study. Clin Chem 2005; 51: 2282-8.